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Latest Blog Posts for Somatic Gene Therapy

  • on Dec 23, 2010
    ...
  • Mesothelioma Claim
    on Dec 15, 2010 in Types of Mesothelioma
    Types Of MesotheliomaMesithelioma disease ...
  • Towards Clinical Applications
    on Dec 1, 2010 in Clinical Applications
    The efficacy of gene therapy will ultimately need to be assessed and demonstrated relative to conventional therapeutics. While it is widely believed that many inborn errors of metabolism may come to be best treated by gene therapy, these will also be...
  • Vectors
    on Dec 1, 2010 in Gene Therapy
    The function of a vector is to control how much of the therapeutic product is produced and where in the body it is produced. Effective gene therapy requires that a therapeutic gene be introduced into cells of the body in a form which allows the gene...
  • Clinical Indications
    on Dec 1, 2010 in Clinical Applications
    The first clinical trials using retroviral vectors demonstrated the feasibility and social and regulatory acceptance of gene transfer into human subject. The initial trials have greatly expanded interest in gene therapy and led to a more focused anal...
  • Conclusion
    on Dec 1, 2010 in Conclusion
    Gene therapies are currently being studied in more than 50 clinical trials. This method holds considerable promise for many inborn errors of metabolism. Gene therapy for inborn errors of metabolism requires the development of biologically sound strat...
  • Current Clinical Trials
    on Dec 1, 2010 in Clinical Applications
    Since the commencement of the first clinical trial involving gene transfer into human subjects in 1989, more than 100 patients have been treated and more than 100 patients have been treated and more than 70 clinical trials are underway. Many of the o...
  • DNA Vector Delivery
    on Dec 1, 2010 in Vector Delivery
    It is also possible to delivery DNA vectors directly to cells withouth the use of viruses. This involves the application of pharmaceutical methods for drug delivery to target DNA vectors to specific cells after direct administration to patients and...
  • Cell Based Therapy
    on Dec 1, 2010 in Vector Delivery
    Organ transplantation in itself o form of gene therapy in which alloogenic cells containing a normal gene are implanted into the body. Genetic manipulation may be used to enchance transplantation therapy, both, by allowing genetic correction of autol...
  • Viral Vector Delivery
    on Dec 1, 2010 in Vector Delivery
    The initial strategies for gene therapy involved the construction of viral vectors in which the expression vector was packaged into a virus particle that was capable of invecting cells. The premise of developing viral vectors was that it might be pos...
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